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Cannondale Synapse Neo SE 650b Disc E-Road Bike 2021

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Synapse Neo SE 650b Disc E-Road Bike 2021

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Product ID: 1070149

The frame protects from vibrations, big 650b x 47mm tyres smooth out the road or trail and the Bosch Drive Unit smoothly delivers power for perfect assistance on any route making the Cannondale Synapse Neo SE Disc E-Road Bike a perfect option to open up new opportunities for exploring or taking your riding to a new adventurous level.

A cleanly integrated Bosch PowerTube battery ensures that the look is sleek, staying true to road bike style, and the 1X drivetrain with 11-42 gears should ensure that you won't shy away from tackling any climbs. With comfort maximised and the geometry still promoting a snappy and responsive ride, this is a great e-bike for long fun days with genuine all-road capability.

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Product Highlights


Consistent and powerful, this bottom bracket motor unit assists on the longest and hardest rides.


Cannondale's loftiest grade of alloy makes the frame light, laterally stiff and robust.


This gear setup combines a fuss-free single chainring with a wide-ranging 11-speed cassette.


These dependable brakes provide powerful stopping power and control in all conditions.

Cannondale Synapse Neo SE 650b Disc E-Road Bike 2021 

The Cannondale Synapse Neo SE Disc E-Road Bike with big volume 650b x 47mm tyres is the bike for confidently exploring any road and any surface.

The outfront geometry uses a slightly slacker head angle for increased stability at speed, and the sharp-steering 650b wheels will feel nimble and agile should you need to act quickly to avoid an obstacle. The frame features SAVE microsuspension technology that helps to dissipate vibrations from the road, improving comfort and handling when the surface is rough or you decide to cut loose on gravel and unknown back roads.

The Bosch Active Line Plus 250W drive unit delivers power smoothly and silently so that when the road or trail tilts upwards you have the right level of assistance for easy climbing and can maintain smooth and efficient pedal form.

With internal cable routing, rack and mudguard mounts the bike is well set to protect you and vulnerable components from road and gravel filth, prolonging the performance of both your legs and the drivetrain.

The SRAM gears are right for being adventurous with plenty of range for any hills and the powerful SRAM Apex hydraulic disc brakes control speed and stopping no matter the surface.


  • SAVE microsuspension technology in the frame engineering helps to absorb road vibrations and bumps
  • Ai offset drivetrain keeps the chainstays shorter for snappy handling and a stiffer, stronger rear wheel
  • Sporty engaging ride feel balanced with true road bike style, with comfort of a slightly more upright rider position
  • Plush 650b x 47mm tyres will roll over just about anything, smoothing out road and gravel
  • Removable fender bridge lets you add protection when the weather turns foul
  • SRAM 11-42t cassette and 1X 44T crankset is perfect for adventurous riding
  • Internal routing protects cables from dirt and water
  • Powerful flat-mount hydraulic disc brakes

Battery Specification

  • Max Assist: 250w
  • Range: Up to 220km / 137 miles
  • Battery Power: 500Wh

Technical Specification

FRAME Cannondale SmartForm C1 Alloy, removable downtube battery, SAVE, Ai, internal cable routing, flat-mount brake, 142x12 thru-axle, Si kickstand mount, rack/mudguard mounts
FORK Cannondale BallisTec Carbon, 1-1/8" to 1.5" tapered steerer, 55mm offset, flat-mount brake, 12x100 thru-axle, mudguard mounts, hidden cable routing
HANDLEBAR Cannondale 3, 6061 alloy, Compact
GRIPS Cannondale Grip Bar Tape with gel, 3.5mm
STEM Cannondale 3, 6061 alloy, 31.8, 7deg
FRONT BRAKE SRAM Apex hydro disc, 160mm Centerline rotor
REAR BRAKE SRAM Apex hydro disc, 160mm Centerline rotor
BRAKE LEVERS SRAM Apex hydro disc
SHIFT LEVERS SRAM Apex hydro disc, 11-speed
CASSETTE SRAM PG-1130, 11-42, 11-speed
CRANKSET Bosch Gen3 with custom Ai offset & FSA rings, 44T
CHAIN SRAM PC-1110, 11-speed
FRONT WHEEL WTB STi23 TCS 2.0, 28h, tubeless-ready, Formula RX-512 12x100
REAR WHEEL WTB STi23 TCS 2.0, 28h, tubeless-ready, Formula DC-142 12x142
FRONT TYRE WTB Byway TCS, 650b x 47mm, tubeless-ready
REAR TYRE WTB Byway TCS, 650b x 47mm, tubeless-ready
SADDLE Fabric Scoop Radius Sport, steel rails
SEATPOST Cannondale 3, 6061 Alloy, 25.4, 350mm (S-M), 400mm (L-XL)
PEDALS Available to be purchased separately
DRIVE UNIT Bosch Active Line Plus 250W
BATTERY Bosch PowerTube 500Wh
CHARGER Bosch 4a
DISPLAY Bosch Purion
EXTRAS Wheel Sensor

Built, Checked, Tuned and Tested

All our bikes are fully built, checked, tuned and tested by our Cytech qualified mechanics and then securely packaged, ready for delivery. All you have to do is add the pedals (if included), attach the handlebars to the stem and tighten them following the included detailed instructions or by watching our video and using the provided FREE tools. Visit our Bike Assembly page to see how you assemble your new bike once you receive it.

All bikes collected from our shop, are built, tested and ready to ride.

Please note, occasionally, manufacturers may change the specification without notice. Bicycles do not come with pedals unless otherwise specified. Bikes ordered for delivery will not arrive with the pedals installed, please refer to the owners manual and pedal installation guides provided for guidance or contact Customer Care. We do not install accessories to bikes, including mudguards.

Cannondale Synapse Neo SE 650b Disc E-Road Bike 2021 Sizing

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